PRP and Bone Marrow Concentrate (BMC) Injections
Platelet-rich plasma (PRP) and bone marrow concentrate (BMC) are orthobiologic injections. They use material from your own body to support healing in painful joints, tendons and ligaments, often as an alternative to surgery.
Platelet-rich plasma (PRP)
PRP is made from a small sample of your own blood. It is spun in a centrifuge to concentrate the platelets, which carry growth factors involved in tissue repair, and then injected into the injured tendon, ligament, muscle or joint. PRP is most often used for knee osteoarthritis, tennis elbow, rotator cuff and Achilles tendon problems. Read our full PRP guide.
Bone marrow concentrate (BMC)
BMC, also called bone marrow aspirate concentrate (BMAC), starts with a small amount of bone marrow drawn from the back of the hip bone under local anesthetic. The marrow is processed to concentrate its cells and growth factors, then injected into the area that needs healing, usually during the same visit. It is used for joint pain, arthritis, sports injuries and other musculoskeletal problems. It is more involved than PRP and usually costs more.
What to expect
- Evaluation. Your doctor confirms the diagnosis with an exam and imaging.
- Collection. Blood (PRP) or bone marrow (BMC) is drawn and processed on site.
- Guided injection. Ultrasound or fluoroscopy is used to place the injection precisely.
- Recovery. Expect a few days of soreness, then a gradual return to activity, often with physical therapy.
Cost and insurance
PRP and BMC are usually not covered by insurance. Prices vary widely by clinic and region, so ask for a written quote that covers the whole treatment plan, including imaging and follow-up visits.
Frequently asked questions
Is PRP or BMC better?
It depends on your condition and how severe it is. PRP has more research behind it and is less invasive. BMC is sometimes used for more advanced joint damage. A specialist can explain which fits your situation.
How long do results last?
When these treatments work, relief often lasts many months. Some people repeat treatment later.
Who should not have these injections?
People with active infection, certain blood disorders or cancer, or who cannot pause some medications may not be good candidates. Your doctor will review your history.
Find a pain specialist near you
Search our map of pain management and regenerative medicine providers across the U.S.
Other levels of pain treatment
Non-interventional care
Rest, medication, physical therapy, TENS and other first-line treatments.
Shockwave & acoustic wave
Non-invasive pressure-wave therapy for tendon and muscle pain.
Interventional procedures
Nerve blocks, epidural injections, radiofrequency ablation and stimulators.
Regenerative medicine
How PRP, cell-based therapy and shockwave fit together.
Surgical treatment
When surgery makes sense and what it involves.
Non-surgical treatment guides
This page is for general information only and is not medical advice. Talk with a qualified physician about your diagnosis and treatment options.
